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Myasthenia Gravis

Myasthenia gravis (MG) is an autoimmune neuromuscular disease where the post-synpatic signal transmission between nerves and muscle is disturbed. It is characterized by muscle weakness that increases with exercise and improves with inactivity. In ocular MG the weakness is limited to the eye muscles and in generalized MG the weakness is spread to other muscle groups.

Acetylcholine Receptor Antibodies (ARAb) RRA Kit

Radio receptor assay for the determination of acetylcholine receptor blocking antibodies (ARAb) in human plasma and serum. Acetylcholine receptor blocking antibodies are detectable in 80%-90% of patients with generalized MG and approximately 50% with ocular MG.

  • Unique commercial assay using acetylcholine receptors isolated from fresh human muscle.
  • Good correlation between antibody titers and muscle weakness in patients.
  • Excellent reproducibility and more than 20 years experience with MG diagnostics.
  • Measuring range: 0-8 nmol/L
  • Sensitivity: 0.2 nmol/L
  • Sample volume: 20 ul serum or plasma
  • Assay time: 1 x 2h + 1 x 30 min
  • Available in kit sizes of 100 or 30 tubes
  • IVD CE

For more information download the ARAb RRA kit brochure.

Muscle-specific Receptor Tyrosine Kinase (MuSK) Antibody ELISA Kit

ELISA assay for the determination of muscle-specific receptor tyrosine kinase antibodies (MuSK-Ab) in human serum.  The ELISA kit is specifically designed for the diagnosis and management of myasthenia gravis (MG) in seronegative patients.

  • First commercially available ELISA
  • Excellent sensitivity (98.5%) and specificity (100%)
  • Qualitative (cut-off) & quantitative (standard curve) evaluation of results
  • High performance assay: low cross-reactivity, good linearity and high precision
  • Measuring range: 0-12 U/ml
  • Sample volume: 10 ul serum
  • Assay time: 3 x 1h + 1 x 30 min
  • Kit size: 12 x 8 strip format
  • IVD CE

For more information download the MuSK-Ab ELISA kit and Autoimmunity brochures.

Product Description Product Code
Acetylcholine Receptor Antibodies (ARAb) RRA